Publications

Selected Publications

Nigam S, Zhu M, Shoemaker AH, Gross AC, Fox CK, Thaker VV. Novel model of childhood appetitive traits in children with obesity. Int J Obes (Lond). 2025 Mar 27. doi: 10.1038/s41366-025-01747-z. Epub ahead of print. PMID: 40148561.

Lardieri A, Thaker VV, Citron-Zafrin K, Garvin JH, Zacharoulis S, Ladas EJ. Pharmacologic Management of Obesity in Neuro-Oncology: A Case Report. Case Rep Oncol. 2024 Dec 17;18(1):169-173. doi: 10.1159/000543178. PMID: 39980512; PMCID: PMC11785398.

Thaker VV, Ebrahim N, Khadegi A, Deng S, Qian K, Yao Z, Thaker S, May B, Patibandala N, Lopez-Pintado S. Classification of childhood obesity using longitudinal clinical body mass index and its validation. Res Sq [Preprint]. 2024 Dec 16:rs.3.rs-5392188. doi: 10.21203/rs.3.rs-5392188/v1. PMID: 39764101; PMCID: PMC11702781.

Rajamoorthi A, Zheng H, Skowronski AA, Zork N, Reddy UM, Tung PW, Kupsco A, Gallagher D, Salem RM, Leibel RL, LeDuc CA, Thaker VV. Association of gestational and childhood circulating C-peptide concentrations in the hyperglycemia and adverse pregnancy outcomes follow-up study. Diabetes Res Clin Pract. 2025 Feb;220:111967. doi: 10.1016/j.diabres.2024.111967. Epub 2024 Dec 21. PMID: 39716665; PMCID: PMC11840794.

Semenova E, Guo A, Liang H, Hernandez CJ, John EB, Thaker VV. The expanding landscape of genetic causes of obesity. Pediatr Res. 2024 Dec 17. doi: 10.1038/s41390-024-03780-6. Epub ahead of print. PMID: 39690244.

Sena C, Della Torre J, Garg E, Zheng H, Partida I, Thaker SK, Woo Baidal J, Shamsian DV, Rausch JC, Thaker VV. Psychological attributes and eating behaviors in 5- to 12-year-old children during periods of stress. Obesity (Silver Spring). 2025 Jan;33(1):134-145. doi: 10.1002/oby.24197. Epub 2024 Dec 16. PMID: 39682059.

Hilaire MJ, Babcock A, White G, Masson CF, Salem RM, Reddy UM, Gallagher D, LeDuc CA, Thaker VV. The association of higher offspring early-childhood weight gain with prepregnancy metabolic and bariatric surgery. Obesity (Silver Spring). 2024 Nov;32(11):2012-2023. doi: 10.1002/oby.24166. PMID: 39497631; PMCID: PMC11694145.

Untalan M, A Crimmins N, Yates KP, A Mencin A, A Xanthakos S, Thaker VV. Prevalence of subclinical hypothyroidism and longitudinal thyroid-stimulating hormone changes in youth with metabolic dysfunction-associated steatotic liver disease: An observational study. Hepatology. 2024 Sep 18:10.1097/HEP.0000000000001095. doi: 10.1097/HEP.0000000000001095. Epub ahead of print. PMID: 39292865; PMCID: PMC11955797.

Tung PW, Thaker VV, Gallagher D, Kupsco A. Mitochondrial Health Markers and Obesity-Related Health in Human Population Studies: A Narrative Review of Recent Literature. Curr Obes Rep. 2024 Dec;13(4):724-738. doi: 10.1007/s13679-024-00588-7. Epub 2024 Sep 17. PMID: 39287712.

Zuccaro MV, LeDuc CA, Thaker VV. Updates on Rare Genetic Variants, Genetic Testing, and Gene Therapy in Individuals With Obesity. Curr Obes Rep. 2024 Sep;13(3):626-641. doi: 10.1007/s13679-024-00567-y. Epub 2024 Jun 1. PMID: 38822963; PMCID: PMC11694263.

Thaker VV, Osganian SK, de Ferranti SD, Sonneville KR, Cheng JK, Feldman HA, Richmond TK. Behavioral and Clinical correlates of children with overweight and obesity, 18 July 2019. Preprint (Version 1) available at Research Square, https://doi.org/10.21203/rs.2.11692/v1.

Thaker VV, Lage AE, Kumari G, Silvera VM, Cohen LE. Clinical Course of Nonfunctional Pituitary Microadenoma in Children: A Single-Center Experience. J Clin Endocrinol Metab. 2019 Dec 1;104(12):5906-5912. doi: 10.1210/jc.2019-01252. PubMed PMID: 31390015; PubMed Central PMCID: PMC6800531.

Ranzenhofer LM, Mayer LES, Davis HA, Mielke-Maday HK, McInerney H, Korn R, Gupta N, Brown AJ, Schebendach J, Tanofsky-Kraff M, Thaker VV, Chung WK, Leibel RL, Walsh BT, Rosenbaum M. The FTO Gene and Measured Food Intake in 5- to10-Year-Old Children Without Obesity. Obesity (Silver Spring). 2019 Jun;27(6):1023-1029. doi: 10.1002/oby.22464. PubMed PMID: 31119882; PubMed Central PMCID: PMC6561098.

De Rosa MC, Chesi A, McCormack S, Zhou J, Weaver B, McDonald M, Christensen S, Liimatta K, Rosenbaum M, Hakonarson H, Doege CA, Grant SFA, Hirschhorn JN, Thaker VV. Characterization of Rare Variants in MC4R in African American and Latino Children With Severe Early-Onset Obesity. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2961-2970. doi: 10.1210/jc.2018-02657. PubMed PMID: 30811542; PubMed Central PMCID: PMC6546308.

Thaker VV, Carter B, Putman M. Recombinant growth hormone therapy for cystic fibrosis in children and young adults. Cochrane Database Syst Rev. 2018 Dec 17;12:CD008901. doi: 10.1002/14651858.CD008901.pub4. PubMed PMID: 30557452; PubMed Central PMCID: PMC6517261.

De Rosa MC, Chesi A, McCormack S, Zhou J, Weaver B, McDonald M, Christensen S, Liimatta K, Rosenbaum M, Hakonarson H, Doege CA, Grant SFA, Hirschhorn JN, Thaker VV. Characterization of rare variants in MC4R in African American and/or Latino children with severe early onset obesity. JCEM. 2019 Feb 27. doi: 10.1210/jc.2018-02657. [Epub ahead of print] PMID: 30811542.

Quarta C, Fisette A, Xu Y, Colldén G, Legutko B, Tseng Y, Reim A, Wierer M, De Rosa MC, Klaus V, Rausch R, Thaker VV, Graf E, Strom TM, Poher A, Gruber T, Le Thuc O, Cebrian-Serrano A, Kabra D, Bellocchio L, Woods SC, Pflugfelder GO, Nogueiras R, Zeltser L, Grunwald Kadow IC, Moon A, García-Cáceres C, Mann M, Treier M, Doege CA, Tschöp MH. Functional identity of hypothalamic melanocortin neurons depends on Tbx3. Nature Metabolism. 2019;1(2):222-235. PMID pending.

Thaker VV. Genetic and Epigenetic Causes of Obesity. Adolesc Med State Art Rev. 2017 Fall;28(2):379-405. Review. PubMed PMID: 30416642; PubMed Central PMCID: PMC6226269.

Lingren T, Thaker VV, Brady C, Namjou B, Kennebeck S, Bickel J, Patibandla N, Ni Y, Van Driest SL, Chen L, Roach A, Cobb B, Kirby J, Denny J, Bailey-Davis L, Williams MS, Marsolo K, Solti I, Holm IA, Harley J, Kohane IS, Savova G, Crimmins N. Developing an Algorithm to Detect Early Childhood Obesity in Two Tertiary Pediatric Medical Centers. Appl Clin Inform. 2016 Jul 20;7(3):693-706. doi: 10.4338/ACI-2016-01-RA-0015. PubMed PMID: 27452794; PubMed Central PMCID: PMC5052543.

Thaker VV, Esteves KM, Towne MC, Brownstein CA, James PM, Crowley L, Hirschhorn JN, Elsea SH, Beggs AH, Picker J, Agrawal PB. Whole exome sequencing identifies RAI1 mutation in a morbidly obese child diagnosed with ROHHAD syndrome. J Clin Endocrinol Metab. 2015 May;100(5):1723-30. doi: 10.1210/jc.2014-4215. Epub 2015 Mar 17. PubMed PMID: 25781356; PubMed Central PMCID: PMC4422892.

Gala S, De Rosa MC, Su Q, Le Duc C, Rausch R, Xin Y, Gromada J, Altarejos J, Leibel R, Doege C, Thaker VV, Stratigopoulos G. Harnessing Single Cell Technology to Understand the Biology of Rpgrip1L on Obesity. New York City Regional Obesity Forum; 2018 September; New York, New York, United States. c.

Thaker VV, Qian K, McDonald M, Christensen S, Lage A, Challa S, Weaver B, Vedantam S, Lopez-Pintado S, Hirschhorn J. Association of Longitudinal Body Mass Index (BMI) Trajectories with Genetic Risk Score in Children with Severe Early Childhood Obesity (SECO). ASHG Abstracts. American Society of Human Genetics; 2018 October; San Diego, CA, United States. c.

Thaker VV, McDonald M, Banks M, Lage A, Osganian S. Demographic and Longitudinal Trends in Children with Severe Early Onset Obesity. American Diabetes Association; 2015 June; Boston, MA. c00.

Thaker VV, Weaver B, McDonald M, Christensen S, Guo M, Picker J, Fleischman AD, Hirschhorn JN. Rare Genetic Variants in Children with Severe Early Onset Obesity. The Endocrine Society Meeting; 2017 April 1; Orlando, Florida, United States. c.

Thaker VV, Hoffman A, Shoemaker A, McDonald M, Christensen S, Banks M, Weaver B, Hirschhorn J, Osganian S. Novel Model of the Child Eating Behavior Questionnaire in Children with Severe Early Onset Obesity. The Obesity Society; 2017 October 31; Washington DC. c.

A full list of publications can be found here.