CBM Mutation Registry

The CBM Complex Database describes germline variants and the associated clinical phenotypes generated by the CBM Complex in Atopy Project. The database is an initiative to serve the medical and research community by offering a comprehensive compilation of information about CARD11, BCL10 and MALT1 genetic variants, common and rare, in the context of immune and allergic disorders. The collection of information contains genotype, phenotype, population frequency and other annotations, functional study results, pathogenicity classifications and publications, when relevant.

The CBM Complex in Atopy project focuses on mechanistic and therapeutic insights into genetic and environmental disruptions of the CBM complex that cause allergy, common and rare.