Hematology, Oncology, and Stem Cell Transplantation

The Division of Hematology, Oncology, and Stem Cell Transplantation’s more than 30 faculty members and 75 staff provide compassionate state-of-the-art care, perform cutting-edge, extramurally supported research, and train the next generation of leaders in our field.

Clinical Services

We are home to the largest and most comprehensive pediatric oncology program in the tri-state area and one of the largest centers in the nation for stem cell and bone marrow transplantation. Our clinical programs include:

• Pediatric Cancer Foundation Developmental Therapeutics Program: The only National Cancer Institute-sponsored Children’s Oncology Group Phase 1 Consortium site in the New York-New Jersey-Connecticut area and one of the founding members of the Therapeutic Approaches to Childhood Leukemia (TACL) consortium.
• Pediatric Liver Cancer Program: With four board-certified pediatric gastrointestinal transplant specialists, we have performed more than twice as many pediatric liver transplants as any other program in the region.
• Precision in Pediatric Sequencing (PIPseq) Program: Our PIPseq program is one of a few in the U.S. and the only one in New York to prospectively sequence cancers, create personalized avatars, and use the results to make clinical decisions.
• Sickle Cell Disease: We are a site for the national collaborative study of gene therapy for SCA, CLIMB: SCD-121, and CLIMB: THAL-111 for patients with severe b-Thalassemia.
• Stem Cell Transplantation Program
• Center for Comprehensive Wellness (CCW): The CCW assimilates integrative treatments into each patient’s care and conducts research on the patterns of use and overall effectiveness of complementary and alternative medicine and nutrition throughout the world.
• Center for Survivor Wellness: We provide continuity of care to address the ongoing impact of cancer treatment on the family, relationships, body image, school, and employment.

Research

With NIH funding, faculty members in the division conduct basic research on the causes of leukemia and brain tumors and have identified new genetic changes resulting in cancer formation. We are also investigating the mechanisms that enable leukemia cells to evade the immune system in the bone marrow.

Members of our translational research division have advanced several new therapeutic approaches for pediatric leukemia, brain tumors, sarcomas, and neuroblastoma. We also have active studies aimed at improving the treatment of childhood blood disorders, including bleeding disorders, iron deficiency anemia, and sickle cell disease.

We maintain a large number of clinical trials that provide bone marrow transplantation for children with cancer and blood disorders. We are studying approaches that may help improve control of symptoms in children with sickle cell disease as well as define methods to cure the disease. Our clinical research program brings the latest therapies to every child that we treat, and our precision medicine program allows us to tailor therapies based on state-of-the-art technologies.

Education

We provide clinical training and research opportunities to medical students and residents. Our three-year Oncology, Hematology, and Stem Cell Transplantation Fellowship Program has both a clinical and research focus.